This handbook is intended for use by university administrators, faculty, students, and higher education partners. The main aim of the handbook is to shine a light on the ways in which teaching and learning processes can be designed to reflect and promote human rights. We explore these opportunities through HRBA principles as well as examples from practice. In addition to addressing these practice-oriented aspects of HRBA, the handbook touches upon the premise of the university as a duty bearer, and the targets and potential processes of reform within the university itself.